Determination of metformin and triclosan in sewage sludge using Liquid chromatography-mass spectrometry (LC-MS)

نویسندگان

چکیده

Pharmaceuticals and personal care products (PPCPs) are generally neither totally removed by sewage treatment nor completely destroyed in the environment. Metformin (MET) triclosan (TRI) two compounds PPCPs that have potential to be environmental pollutants. This research aimed determine MET TRI sludge using a liquid chromatograph-mass spectrometer (LCMS-8040) extraction method. The Milli-Q water were also tested at three different concentrations (0.01, 0.02, 0.03 mg L-1). As result, corresponding recoveries of both matrixes ranged from 85.93 116.10 per cent 90.50 116.30 (n = 7, RSD < 10%). Then, limit detection (LOD) quantification (LOQ) for found 0.005 0.01 L-1. amounts samples Ukkadam plant (USTP), Coimbatore, BDL 0.0587 L-1 0.0719 0.1851 L-1, respectively. Consequently, Tamil Nadu Agricultural University (TSTP), 0.0227 0.0393 0.1296 exclusive use highly sensitive LCMS-8040 consumes less time than other analytical methods measuring amount overcoming risk chemical degradation.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Validation of the analysis method of 25 pesticide residues in rice using LC-MS/MS device (liquid chromatography-mass spectrometry)

Introduction: In recent years, due to the increase in the use of pesticides in agricultural products and its entry into the human food chain, there has been an increase in concerns about the health of food among people. Therefore, the purpose of conducting this research is to validate the analysis method. 25 pesticide residues in rice using LC-MS/MS. Methods: In this research, a simultaneous an...

متن کامل

Determination of starch lysophospholipids in rice using liquid chromatography-mass spectrometry (LC-MS).

Acquiring a complete understanding of rice starch lysophospholipids (LPLs), their biosynthetic pathways and genetic diversity, and the influence of genotype by environment interactions has been hampered by the lack of efficient high-throughput extraction and analysis methods. It was hypothesized a single-step aqueous n-propanol extraction combined with liquid chromatography-mass spectrometry (L...

متن کامل

Liquid chromatography–tandem mass spectrometry (LC-MS) method for the assignment of enalapril and enalaprilat in human plasma

A rapid and sensitive liquid chromatography–tandem mass spectrometry (LC-MS) method was developed for the determination of enalapril and enalaprilat in human plasma. Detection of analytes was achieved by tandem mass spectrometry with electrospray ionization (ESI) interface in positive ion mode which was operated under the multiple-reaction monitoring mode. Sample pretreatment was involved...

متن کامل

pharmacokinetics and bioequivalence of methotrexate in human plasma studied by liquid chromatography-mass spectrometry (lc-ms)

background methotrexate is a folic acid antagonist that has been in clinical use for five decades. its use in patients with brain tumors is primarily confined to primary central nervous system lymphoma (pcnsl), in which it is the cornerstone of chemotherapy. objectives a selective and sensitive high-performance liquid chromatography-electrospray ionization-mass spectrometry method was developed...

متن کامل

A quick and Sensitive Liquid Chromatography–tandem Mass Spectrometry (LC-MS) Method for the Determination of Enalapril and Enalaprilat in Human Plasma: Application to a Bioequivalence Study

A rapid and sensitive liquid chromatography–tandem mass spectrometry (LC-MS) method for the estimation of enalapril and enalaprilat in human plasma. Detection of analytes was achieved by tandem mass spectrometry with electrospray ionization (ESI) interface in positive ion mode was operated under the multiple-reaction monitoring mode. Sample pretreatment involved in a one-step protein precipitat...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Applied and Natural Science

سال: 2022

ISSN: ['0974-9411', '2231-5209']

DOI: https://doi.org/10.31018/jans.v14i4.3906